Decreased levels of serum soluble HLA class I antigens in HLA-B27 positive spondyloarthropathies.
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چکیده
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Human class I major histocompatibility complex allele HLA-B27 is associated with a group of human diseases called "spondyloarthropathies." Studies on transgenic rats expressing HLA-B27 and human beta 2-microglobulin have confirmed the role of HLA-B27 in disease pathogenesis. Here we report spontaneous inflammatory arthritis in HLA-B27 transgenic mice lacking beta 2-microglobulin (B27+ beta 2m-/...
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ورودعنوان ژورنال:
- Annals of the rheumatic diseases
دوره 65 2 شماره
صفحات -
تاریخ انتشار 2006